Do you use CRISPR?


CRISPR is an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, good thing there is an acronym!

The CRISPR/Cas9 system is a genomic editing tool that allows for efficient easy editing of genetic material. As described in the below video CRISPR/Cas9 is like a microscopic pair of scissors that enable DNA segments to be removed and replaced.

A short video from STAT provides an introduction to the CRISPR tool.

What role will CRISPR play in eliminating genetic based diseases in the future?

NEW CRISPR news – As reported by Science Daily, researchers from Duke University have successfully used CRISPR to edit mouse connective tissue into nuronal cells. As reported in the article:
“This technique has many applications for science and medicine. For example, we might have a general idea of how most people’s neurons will respond to a drug, but we don’t know how your particular neurons with your particular genetics will respond,” said Charles Gersbach, the Rooney Family Associate Professor of Biomedical Engineering and director for the Center of Biomolecular and Tissue Engineering at Duke. “Taking biopsies of your brain to test your neurons is not an option. But if we could take a skin cell from your arm, turn it into a neuron, and then treat it with various drug combinations, we could determine an optimal personalized therapy.”

“The challenge is efficiently generating neurons that are stable and have a genetic programming that looks like your real neurons,” says Joshua Black, the graduate student in Gersbach’s lab who led the work. “That has been a major obstacle in this area.”